邢唷> 欹'` 瀗bjbj鲟鲟 <攰攰]=h Z Z Z n ///8J/</tn p^.00.4040J0424242UUUU1AUQYa]$瀇hb匽Z YL22"YLYL匽 40J0*^鸖鸖鸖YL 40840U鸖YLU鸖鸖VT B ~T40/ )6/UNXnT襎<@^0p^vT頱璔頱~T頱Z ~TT42;X鸖nA侳424242匽匽S|424242p^YLYLYLYLn n n $/n n n /n n n   March 28, 2013 PRIVATE  CURRICULUM VITAE Name: Barry W. Potvin, Ph.D.Citizenship: U.S.A.Business: Department of Biology Yeshiva College 2495 Amsterdam Avenue New York, New York l0033Business Telephone: (212) 9605372 Education University of North Carolina Ph.D., Genetics December, 1973 Chapel Hill, North Carolina Brandeis University B.A., Biology June, l968 Waltham, MassachusettsMilitary Service: 19731975 Senior Medical Laboratory Technician U.S. Army Reserve 19691973 Medical Laboratory Technician U.S. Army Reserve Honorable Discharge, February 1975 Professional Society Memberships: New York Academy of Sciences Prior Experience: 2000-present Professor, Department of Biology, Yeshiva College 1990-2000 Associate Professor, Department of Biology, Yeshiva College 19801990 Assistant Professor, Department of Biology, Yeshiva College -Tenure granted 9/1/86 1989-present Visiting Professor, Department of Cell Biology, Albert Einstein College of Medicine 2008 Biomedical Research Careers Advisor 2004-2007 Director of Pre-Health Advisement, J9UJX Mart - Highly rated Sterling 762x39 123gr FMJ (1000rd) Steel-cased bulk Positive feedback 19841989 PreHealth Sciences Advisor, J9UJX Mart - Highly rated Sterling 762x39 123gr FMJ (1000rd) Steel-cased bulk Positive feedback 1988-1989 Research Fellow, Department of Cell Biology, Albert Einstein College of Medicine 1981l987 Adjunct Associate Research Scientist, Department of Biochemistry, College of Physicians and Surgeons, Columbia University 19771980 Instructor, Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University 19741977 Postdoctoral Fellow, Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University 19731974 Staff Associate, Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University 19671968 Laboratory Assistant, Genetics Laboratory, Brandeis University 1967 Teaching Assistant, Biology Laboratory, Brandeis University 1967, 1966 Biological Aide, Population Dynamics Division, United States Bureau of Commercial Fisheries, Woods Hole, Massachusetts (summer positions)Fellowships and Awards: 1988 American Cancer Society Scholar Grant to partially support a one-year sabbatical leave for research conducted at the Cell Biology Department of the Albert Einstein College of Medicine. 1985 J9UJX Mart - Highly rated Sterling 762x39 123gr FMJ (1000rd) Steel-cased bulk Positive feedback High School Research Program. An award of $5,000 to enable high school students To acquire laboratory research experience. 1984 Mellon Foundation Award to develop a Biochemistry Laboratory Course. 1983 Mellon Foundation Award to attend a laboratory workshop in Recombinant DNA Methodology 19821984 Cottrell College Science Grant to support a project entitled: "Selection of cells which synthesize inappropriate products" (2 year award of $20,000 from Research Corporation). 1981 Mellon Foundation Award to support study in Somatic Cell Hybridization and Gene Transfer at the Cell Science Center, Lake Placid, New York 19741977 N.I.H. Postdoctoral Fellowship, Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University 19731974 Matheson Foundation Postdoctoral Award, Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University 19681973 N.I.H. Predoctoral Fellowship, Curriculum in Genetics, University of North Carolina at Chapel Hill Publications:Potvin, Barry W. and Harry Gooder. 1975. Carbamyl phosphate synthesis Bacillus subtilis. Biochemical Genetics 13(12): 125143.Potvin, Barry W., Raymond J. Kelleher and Harry Gooder. 1975. The pyrimidine biosynthetic pathway of Bacillus subtilis. Journal of Bacteriology 123(2): 604615.Potvin, Barry W., Harvey J. Stern, S. Randolph May, George F.M. Lam and Robert S. Krooth. 1978. Inhibition by barbituric acid and its derivative of the enzymes in rat brain which participate in the synthesis of pyrimidine ribotides. Biochemical Pharmacology 27(5): 655665.Krooth, Robert S., WenLuan Hsiao and Barry W. Potvin. 1979. Resistance to 5fluoroorotic acid and pyrimidine auxotrophy: a new bidirectional selective system for mammalian cells. Somatic Cell Genetics 5 (5): 551 569.Komura, H., K. Nakanishi, B.W. Potvin, H.J. Stern and R.S. Krooth. 1980. Orotidine 5'monophosphate decarboxylase inhibitors formed by spontaneous reaction of barbituric acid and ribose 5phosphate, a surprising reaction. Journal of the American Chemical Society 102(3): 12081210.Potvin, B., D. Howard, R. Kumar, and P. Stanley. l988. Apparent activation of endogenous a(1,3)fucosyltransferase genes by transfection of DNA into Chinese Hamster Ovary Cells. Journal of Cell Biology 107(6):851a (Abstract) Potvin, Barry, Ravindra Kumar, Daniel Howard, and Pamela Stanley. 1990. Transfection of a human a(1,3)fucosyltransferase gene into Chinese hamster ovary cells: complications arise from activation of endogenous a(1,3)fucosyltransferases. Journal of Biological Chemistry 265(3):1615-1622. Kumar, Ravindra, Barry Potvin, William A. Muller and Pamela Stanley. 1991. Cloning of a human a(1,3)-fucosyltransferase gene that encodes ELFT but does not confer ELAM-1 recognition on Chinese hamster ovary cell transfectants. Journal of Biological Chemistry 266(32):21777-21783. Potvin, Barry and Pamela Stanley. 1991. Activation of two new a(1,3)fucosyltransferase activities in Chinese hamster ovary cells by 5-azacytidine. Cell Regulation 2:989-1000. Stanley, Pamela and Barry Potvin. 1992. Mammalian a(1,3)fucosyltransferases: How many are there? Journal of Cellular Biochemistry 16D:149.(Abstract) Potvin, Barry, Diana Yoon and Pamela Stanley. (1993). Identification of new a(1,3)fucosyltransferase activities of CHO cells. Journal of Cellular Biochemistry 17A:373.(Abstract) Goelz, Susan, Ravindra Kumar, Barry Potvin, Subha Sundaram, Margot Brickelmaier, and Pamela Stanley. 1994. Differential expression of an E-Selectin ligand (SLex) by two Chinese Hamster Ovary cell lines transfected with the same a(1,3)fucosyltransferase gene (ELFT). Journal of Biological Chemistry 269(2):1033-1040. Stockert,Richard, Barry Potvin, Lian Tao, Pamela Stanley, and Allan Wolkoff. 1995. Human Hepatoma Cell Mutant Defective in Cell Surface Protein Trafficking. Journal of Biological Chemistry 270(27):16107-16113.Potvin, Barry, T. Shantha Raju, and Pamela Stanley. 1995. lec32: A New Mutation in CHO Cells that Abrogates CMP-Sialic Acid Synthetase Activity. Glycoconjugate Journal 12(4):517 (Abstract).Potvin, Barry, T. Shantha Raju, and Pamela Stanley. 1995. lec32 is a New Mutation in Chinese Hamster Ovary Cells That Essentially Abrogates CMP-N-acetylneuraminic Acid Synthetase Activity. Journal of Biological Chemistry 270(51):30415-30421.Stanley, Pamela, T.S. Raju, E. Ioffe, A. Zhang, B. Potvin, R. Kumar, Y. Liu, and S. Sundaram. 1997. Glycosyltransferase Mutants of Mice and CHO Cells Reveal Functions of Mammalian Glycans. FASEB Journal 11(9):A1443 (Abstract).Ravi Kumar, Ron Kriz, Mark Stahl, Mark Proia, Kevin Bean, Barry Potvin, and Francis Sullivan. 1997. Cloning of Human GDP-D-mannose-4,6-dehydratase Gene. Glycobiology 7(7):1029 (Abstract).Sullivan, Francis, Ravindra Kumar, Ronald Kriz, Mark Stahl, Guang-Yi XU, Jason Rouse, Xiao-jia Chang, Amechand Boodhoo, Barry Potvin, and Dale Cumming. 1998. Molecular Cloning of Human GDP-mannose 4,6-Dehydratase and Reconstitution of GDP-fucose Biosynthesis in Vitro. Journal of Biological Chemistry 273(14):8193-8202.M(nster, A., M. Eckhardt, B. Potvin, M. M(hlenhoff, P. Stanley, and R. Gerardy-Schahn. 1998. Mammalian CMP-NeuAc Synthetase. International Carbohydrate Symposium Abstract Book CP024. (Abstract).M(nster, Anja-K, Matthias Eckhardt, Barry Potvin, Martina M(hlenhoff, Pamela Stanley, and Rita Gerardy-Schahn. 1998. Mammalian Cytidine 5-monophosphate N-acetyneuraminic Acid Synthetase: A Nuclear Protein with Evolutionarily Conserved Structural Motifs. Proceedings of the National Academy of Sciences (USA) 95:9140-9145.Zhang,Aimin, Barry Potvin, Ari Zaiman, Ravindra Kumar, Laurie Phillips, and Pamela Stanley. 1999. Loss of a Negative Regulatory Factor Allows Expression of A Human FUT6 Gene Orthologue in Gain-of-Function Mutant LEC11B. Journal of Biological Chemistry 274(15):10439-10450. Shi, Xiaoying, Barry Potvin, Tianmin Huang, Philip Hilgard, David C. Spray, Sylvia O. Suadicani, Allan W. Wolkoff, Pamela Stanley and Richard J. Stockert. 2001. A Novel Casein Kinase 2 ( Subunit Regulates Membrane Protein Traffic in the Human Hepatoma Cell Line HUH7. Journal of Biological Chemistry, 276(3):2075-2082.Patnaik, Santosh K., Barry Potvin and Pamela Stanley. 2004. LEC12 and LEC29 Gain-of-Function CHO Mutants Reveal Mechanisms for Regulating VIM-2 Antigen Synthesis and E-Selectin Binding. Journal of Biological Chemistry, 279(48): 49716-49726.Patnaik, Santosh Kumar, Barry Potvin, Susanne Carlsson, David Sturm, Hakon Leffler, and Pamela Stanley. 2006. Complex N-glycans are the Major Ligands for Galectin-1, Galectin-3 and Galectin-8 on Chinese Hamster Ovary Cells. Glycobiology, 16: 305-317. Stockert, Richard, Barry Potvin, Sangeeta Nath, Allan Wolkoff, and Pamela Stanley. 2007. New Liver Cell Mutants Defective in the Endocytic Pathway. Biochimica and Biophysica Acta Biomembranes, 1768(7): 1741-1749.Doctoral Dissertation:The de novo pyrimidine biosynthetic pathway of Bacillus subtilis. I. Carbamyl phosphate synthetase. II. Biochemical and genetic aspects of the pathway.(Under the direction of Dr. Harry Gooder). Current Research Activities: RNAi-knockdown of glycosylation-related genes and its effects on the development of c. elegans. Presentations:February, 1973, Genetics Division, Massachusetts General Hospital, The Pyrimidine Biosynthetic Pathway of Bacillus subtilis:February, 1973, Department of Human Genetics and Development, Columbia College of Physicians & Surgeons, The Pyrimidine Biosynthetic Pathway of Bacillus subtilis.January, 1976, Department of Genetics, University of Hawaii, The Pyrimidine Biosynthetic Pathway of Normal and Orotic Aciduric Human FibroblastsApril, 1976, Department of Biochemistry and Biophysics, Texas A&M University, The Pyrimidine Biosynthetic Pathway of Normal and Orotic Aciduric Human Fibroblasts.October, 1976, Department of Biochemistry and Biophysics, University of Rhode Island, The Pyrimidine Biosynthetic Pathway of Normal and Orotic Aciduric Human Fibroblasts. December, 1977, Cancer Research Center, Columbia College of Physicians and Surgeons, Resistance to 5Fluoroorotic Acid and 5Fluorouracil in Murine Erythroleukemic Cells.May, 1978, Curriculum in Genetics, University of North Carolina, Resistance to 5Fluoroorotic Acid and 5Fluorouracil in Murine Erythroleukemic Cells.March, 1980, Biology Department, Rutgers University (Douglass College), Resistance to 5Fluoroorotic Acid and 5Fluorouracil in Murine Erythro leukemic Cells. March, 1984, Sigma XI Society, Ramapo College, Mutation, Drug Resistance,and Oncogenic Virulence.February, 1989, Annual Meeting of the American Society for Cell Biology and the American Society for Biochemistry and Molecular Biology, San Francisco California, Apparent activation of the endogenous ((1,3)fucosyltransferase genes by transfection of DNA into Chinese Hamster Ovary Cells. November, 1989, Department of Cell Biology, Albert Einstein College of Medicine of Yeshiva University, Transfection of a Human Gene Encoding a(1,3) Fucosyltransferase into Chinese Hamster Ovary Cells. February, 1990, Curriculum in Genetics, The University of North Carolina at Chapel Hill, Transfection of a Human Gene Encoding a(1,3)Fucosyltransferase into Chinese Hamster Ovary Cells. April, 1990, Sigma Delta Rho Society, Yeshiva and Stern Colleges, Probing the Secrets of Development and Cancer. July, 1991, 11th International Symposium on Glycoconjugates, Toronto, Canada, 5-Azacytidine Induces Expression of Two, Apparently Novel, a(1,3)Fucosyltransferase Activities in CHO Cells. September, 1991, Department of Cell Biology, Albert Einstein College of Medicine of Yeshiva University, a(1,3)Fucosyltransferases that Synthesize Ligands for Cell Adhesion Molecules. October, 1995, Department of Cell Bio!AGHPQR @ R ~  % @ W v &Wg$Vi鲰漩帐徽龀雳鰺雳雳鰺燊燊燊燊桍拵拵拵妿妿鰱燊妿鰺鰺鰺h7 h`-hFh秪|5丂堼CJh7 5丂堼CJh`-5>*@堼CJh`-@堼CJjh`-5丂堼Uh`-5丂堼CJjh`-5丂堼CJUh鵸f5丂堼CJh:5丂堼CJh`-5丂堼CJ6ST 0 [  $ % i *$gd7 $ *$a$ $ *$a$gd7 n卬唍漬  7 a b ? @ ~ $ %  *$gd7 *$gd7 $  *$a$ $ *$a$% VWV}~12 $$ @ a$gd7 @ *$gd7 $$ a$gd7 *$gd秪| *$gd7 $$ 凘 劺鬪凘 `劺鬭$gd7 $$ 繿$gd7 $$ a$gd7 $$  @ a$gd7 i~12DYxSq!-.<op$CWvGK5d{57Fc}(*鲵铗铗铞弼弼弼弼弼弼弼铗铗铗铞邛仰仰撒弼弼仰仰铞念念鲒鲒鲒鲒鲒鲒鲒鲒龇鲒h`-5丂堼CJOJQJh銳h秪|5丂堼CJh銳5丂堼CJh`-5>*@堼CJh7 5丂堼CJh`-h7 h`-5丂堼CJH2,- $  *$a$ $ *$a$ $$ *a$gd7  * 勬 *$^勬 `鮣d7 @ *$gd7 * *$gd7 *$gdF  *$gdF *$gd7  @ *$gd7 GstLM4557%$a$gdF  *$gdF$  *$a$gd7 $ *$a$ $  *$a$$  *$a$gd銳7:;T!V!##$$$& $ *$a$ *$gdF$$ 勬 鮚勬 `鮝$gd銳 0!6!""\#b#$$$$N%P%%%&&V'^'((H)J)))**++l,o,M-O- . .&/./P/S/e/f///)0*0c0d0]1_122h2k293:333445555鲩鲩鲛鲩鲛鲩鲛鲩鲛鲩鲛鲇鲩鲛鲛鋈鲛鲛鲛鋈鲛黾黾黾黾鲛鋈鲛霭鲛鲛鲛雩hF5丂堼CJ jah`-5丂堼CJ jh`-5丂堼CJh`-56丂堼CJh`-5丂堼CJH*h`-5>*@堼CJh`-5丂堼CJOJQJh`-5丂堼CJB&&|'~'())**++,,e-f-".#.c/d/'0(0k1l1~223344 *$gdF45566666c7d7e777777777z8{89 999U:V:; *$gd鵸f *$gdF5s6z66666666787e777777777 8g8x8{88 99#9/9999:::;;;;X;;;<<*>,>??rAtA郈釩EEFd裡觘鲭鲭鲟膂膂做膂卫析膂做膂做膂扶扶扶扶扶扶扶膂烐烐烐烐滝h`-5丂堼CJH*Uh`-5丂堼CJOJQJ jah`-5丂堼CJhF5丂堼CJh凬h凬56丂堼CJh凬5丂堼CJh#5丂堼CJh#5>*@堼CJh`-5>*@堼CJh`-5丂堼CJ9;;;;F<G<<<K=L=>>?r@t@鐰闍藼蜝DDFD碋禘|d}d錮鎑纄  *$gdF *$gdFlogy, Albert Einstein College of Medicine of J9UJX Mart - Highly rated Sterling 762x39 123gr FMJ (1000rd) Steel-cased bulk Positive feedback, Sialic Acid: Functional Significance in Mammalian Glycans.March, 1997, Yeshiva College Spring Academic Colloquia, Sugars: The Dr. Jekyll and Mr. Hyde of Biology.April, 1997, The Curriculum in Genetics, University of North Carolina School of Medicine, Chapel Hill, N.C., Isolation and Characterization of a New Mammalian Cell Mutant Defective in the Synthesis of CMP-Sialic Acid.November,2000, 5th Annual Conference of the Society for Glycobiology, Boston, MA, MALDI-TOF Analysis of N-Glycans of CHO Gain-of-Function Mutants That Express an ((1,3)Fucosyltransferase. Service to the University:2008-2010 Faculty Pre-Health Sciences Advisement Committee2008 Biomedical Research Careers Advisor2004-2007 Director of Pre-Health Advisement2001-2003 Prehealth Sciences Advisement Evaluation Committee (Chairperson)2000-2001 Faculty Evaluation Committee for Dean Norman Adler1997-present Roth Summer Research Fellowship Committee (Chairperson, 1999-present)19841989 PreHealth Sciences Advisor 1982present DNSM Executive Committee1981l988 Academic Standards Committee (Chairperson, 1983l988)2009-2011 Honors Committee2010-present Experimental and Quantitative Methods Course Committee (Chairperson)2011 Biology Search Committee2012-present Public Health Minor Committee (Chairperson) Courses extensively revised or newly introduced:Biology 3513C  Introductory Genetics (Lecture and Laboratory) Biology 3614R+LAdvanced Genetics (Lecture and Laboratory) Biology 3207R+LCellular Physiology (Lecture and Laboratory) Biology 1405C  Research Methods in Biology (Lecture and Laboratory) Biology 1405H -- Honors Research Methods in Biology (Lecture and Laboratory) Biology 1376L  Biochemistry (Laboratory) also listed as Chemistry 1376L Biology 3521A  Molecular Genetics (Lecture) Biology 4933H -- Fundamentals of Public Health (Honors) Biology 4930 -- Epidemiology of infectious Diseases Other teaching experience involving course revisions:Biology 4023R+LMicrobiology (Lecture and Laboratory), fall, 1980, spring, 1987 and fall, 2007 Biology 4931  Current Topics, spring, 1983 Biology 1376R  Biochemistry (Lecture),fall, 1980 and fall, 1992. Also listed as Chemistry 1376R Biology 1377R -- Biochemistry (Lecture), spring, 1993 Also listed as Chemistry 1377R Chemistry 1379 Pharmaceutical Chemistry / Pharmacology, Shared responsibility, spring, 1984 Biology 1376H -- Honors Biochemistry Lecture PAGE  PAGE 2 Curriculum Vitae/Barry W. 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